Commercial Real Estate for Sale and Lease in Santa Ana, CA

Commercial property in Santa Ana, CA

$1,280,000

848 N Parton, Santa Ana, CA

Office · 2,888 sqft · Built 1966 · 6,970 sqft lot

Excellent owner-user opportunity in Santa Ana. Approximately 2,888 SF two-story office building, 6,970 SF lot, situated conveniently located near the Santa Ana Civic Center and…

$1,599,900

502 W 17th Street, Santa Ana, CA

Mixed Use · 6,150 sqft · Built 1952 · 4 units · 9,583 sqft lot

Welcome to an excellent investment and owner-user opportunity in Santa Ana’s established commercial district.

$790,000

1823 W 17th, Santa Ana, CA

Mixed Use · 1,250 sqft · 5,388 sqft lot

Location! Location! 1250 sq ft commercial building close to Santa Ana College, Santa Ana Metrolink Station, the Main Place, Costa Mesa Mall, FWY 5, 22, 55 & 57.

$900,000

1819 W 17th, Santa Ana, CA

Mixed Use · 3,001 sqft · Built 1956 · 5,525 sqft lot

Location! Location! Large 3,001 sq ft commercial building near Santa Ana College, Santa Ana Metrolink Station, the Main Place, Costa Mesa Mall, and FWY 5, 22, 55 & 57.

$800,000

1815 W 17th, Santa Ana, CA

Mixed Use · 2,116 sqft · 5,635 sqft lot

Location! Location! Large 2,116 sq ft commercial building near Santa Ana College, Santa Ana Metrolink Station, the Main Place, Costa Mesa Mall, and FWY 5, 22, 55 & 57.

$925,000

207 W Buffalo Avenue, Santa Ana, CA

Mixed Use · 1,968 sqft · Built 1922 · 2 units · 6,970 sqft lot

Charming, character-rich, and full of upside — this 100-year-old duplex in Santa Ana’s coveted Museum District, adjacent to Floral Park, is a rare find for the savvy investor.

$3,150,000

3514 Westminster, Santa Ana, CA

Mixed Use · 5,950 sqft · Built 1955 · 47,384 sqft lot · Zoned Professional/Mixed Use

Prime Commercial Opportunity in the Heart of Downtown Santa Ana. Now is the time to stake your claim in one of Orange County’s most vibrant and rapidly evolving urban centers.

$2,495

1526 84 Brookhollow, Santa Ana, CA

Office · 1,100 sqft · 1,200 sqft lot

1,100 SF Office Space for Rent in Santa Ana – 1516 Brookhollow Dr #84 GREAT MOVE-IN SPECIAL – DISCOUNTED RENT FOR THE FIRST 3 MONTHS!

$795,000

1852 W 17th, Santa Ana, CA

Mixed Use · 1,896 sqft · Built 1931 · 5558 units · 7,841 sqft lot

First time on the market since 1972, this fabulous commercial/mixed unit building sits right on the 17th Street main business corridor.

$3,350,000

2014 S Main, Santa Ana, CA

Retail · 5,895 sqft · Built 1957 · 4% cap rate · 10,900 sqft lot

Prime Santa Ana Dual-Zoning Portfolio: Income & Development Upside Rare investment opportunity to acquire two contiguous parcels featuring separate zoning and immediate cash flow…

$2,995

1913 E 17th Street 205/206, Santa Ana, CA

Business · Price reduced · 65,445 sqft · Full service lease · Built 1982 · 40 units · 65,340 sqft lot

Discover these exceptional turnkey second-floor commercial condos, thoughtfully designed to support a wide range of professional uses.

$899,999

1902 S Standard, Santa Ana, CA

Mixed Use · 1,000 sqft · 9,148 sqft lot

This multi-use building in the City of Santa Ana offers endless potential for business owners ready to grow, developers looking for their next project, or investors seeking…

$1,734

1535 E 17th Street E 105, Santa Ana, CA

Business · 867 sqft · Modified gross lease · Built 1968 · 15,246 sqft lot

FIRST FLOOR OFFICE #105 WITH PRIVATE BATHROOM...NEW TILE FLOORING...2-3 OFFICES, RECEPTION AREA AND OR STORAGE ROOM...TILE FLOOR...NEWLY REMODELED PROFESSIONAL OFFICE COMPLEX (THE…

$1,800

302 N Tustin Ave 101, Santa Ana, CA

Office · 900 sqft · Modified gross lease · 21,344 sqft lot

EXECUTIVE, PROFESSIONAL OR MEDICAL...900 SQ FT...DOWNSTAIRS...3 OFFICES AND RECEPTION ENTRY...INCLUDES EXTRA LARGE STORAGE ROOM...PRIVATE BATHROOM AND KITCHENETTE...ATTACHED SINGLE…

$2,185

1611 E 4th Street 206, Santa Ana, CA

Office · 971 sqft · Gross lease · 6 units · 25,265 sqft lot

971 SQ FT PROFESSIONAL OFFICE...PLAZA de SANTA ANA...SPANISH STYLE BUILDING WITH COVERED, OPEN AND GATED PARKING...2 STORY BUILDING WITH ELEVATOR...GREAT LOCATION...GROSS…

$2,695

1526 Brookhollow, Santa Ana, CA

Office · 1,100 sqft · Gross lease · 39,291 sqft lot

Santa Ana Brookhollow Office Space GREAT DISCOUNT ON THE FIRST 3 months. 1100 square foot Brookhollow Office space, ready for operations. Office has 2 offices.

$1,875,000

2803 W 17th, Santa Ana, CA

Office · 3,950 sqft · 19 units · 7,405 sqft lot

Prime Corner Commercial Building – Highly Visible Main Street Location Exceptional 2-story upgraded commercial building situated on a busy, high-traffic main street.

$1,149,000

1126 N Flower, Santa Ana, CA

Office · 2,494 sqft · 5,881 sqft lot

Acreage Real Estate proudly presents, commercial Medical Office income property offering a strong opportunity for an owner-user or value-add investor.

$1,750

1715 E Wilshire Avenue 714 & 715, Santa Ana, CA

Office · Price reduced · 32,256 sqft · Full service lease · Built 1988 · 18 units · 73,616 sqft lot · Zoned commerical

NEW TO THE MARKET FOR LEASE! Contemporary flexible office suites offering 1,688 square foot space with large windows, vinyl flooring, functional and efficient layout designed for…

$3,589,000

4521 W 1st, Santa Ana, CA

Industrial · 5,000 sqft · Built 1955 · 27,443 sqft lot

Rare Industrial Opportunity in the Heart of Little Saigon! An exceptional opportunity to own one of the few large industrial properties in the heart of Orange County’s thriving…

$4,500,000

505 S Main, Santa Ana, CA

Mixed Use · 6,550 sqft · Built 1928 · 39,380 sqft lot

505 S Main Street presents a rare opportunity to acquire a high-visibility commercial asset positioned on a commanding hard corner in central Santa Ana.

$350,000

1913 E 17th 204, Santa Ana, CA

Office · Price reduced · 1,165 sqft · Built 1982 · 40 units · 65,445 sqft lot

Discover this exceptional turnkey second-floor commercial condo, thoughtfully designed to support a wide range of professional uses.

$2,750,000

1327 N Main, Santa Ana, CA

Warehouse · 4,500 sqft · Built 1954 · 8,905 sqft lot · Zoned SP3

An exceptional and versatile commercial property that presents an ideal opportunity for both Owner-Users and Investors.?

$1,400

1535 E 17th Street E 107, Santa Ana, CA

Business · 669 sqft · Modified gross lease · Built 1968 · 15,246 sqft lot

PRIVATE BATHROOM...TILE FLOORING...KITCHENETTE...RECEPTION ENTRY...3 PRIVATE OFFICES...NEWLY REMODELED PROFESSIONAL OFFICE COMPLEX (THE ATRIUM) IN A GREAT BUSINESS…

More listings in Santa Ana, CA

What's on the market in Santa Ana right now

Asking prices of listings currently active on Nalren in Santa Ana, CA — refreshed daily.

Commercial property types in Santa Ana

• Office — 8 for sale, 10 for lease · median asking $1,214,500 · for lease
• Retail — 2 for sale, 2 for lease
• Industrial & Warehouse — 4 for sale, 2 for lease · median asking $3,000,000
• Multifamily — 4 for sale · median asking $1,995,000
• Mixed-Use — 13 for sale · median asking $925,000

All 18 commercial spaces for lease in Santa Ana →

Counts and asking prices of listings currently active on Nalren in Santa Ana, CA — refreshed daily. Asking prices, not valuations.

Recently sold commercial properties in Santa Ana, CA

By type: 9 retail, 6 office, 5 mixed-use, 2 land, 2 industrial & warehouse.

Latest closed sales

• 327 W 17th — Sold for $600,000 on Sep 11, 2026 (Retail · 1,500 sqft)
• 1717 S Main Street — Sold for $1,075,000 on Aug 14, 2026 (Retail · 3,920 sqft)
• 1429 W 5th — Sold for $635,000 on Jun 30, 2026 (Retail · 1,836 sqft)
• 1248 E 17th — Sold for $2,800,000 on Jun 25, 2026 (Retail · 2,115 sqft · 5.17% cap rate)
• 1715 W 1st — Sold for $2,337,500 on Jun 11, 2026 (Special Purpose · 436 sqft)
• 606 S Main Street — Sold for $460,000 on Jun 2, 2026 (Mixed Use · 6,098 sqft)
• 1440 S Broadway — Sold for $1,050,000 on May 27, 2026 (1,038 sqft · 5.28% cap rate)
• 19352 Lemon Hill — Sold for $875,000 on Apr 27, 2026 (Land)
• 120 N Hathaway — Sold for $445,000 on Mar 25, 2026 (Industrial · 950 sqft)
• 1820 E Garry Avenue 209-C — Sold for $80,000 on Feb 27, 2026 (Office · 425 sqft)

Sold prices are MLS-reported closed sales recorded in Santa Ana, CA over the last 24 months — not an estimate or valuation of any property.

Commercial real estate in cities near Santa Ana

Commercial real estate guides

Buying, selling, or leasing commercial property in Santa Ana, CA?

Tell us what you're working on and a licensed Nalren agent — or, in some cases, a licensed referral partner — who works commercial real estate reaches out, typically within one business day. Free, no obligation.

Frequently asked questions — Santa Ana, CA

Also in Santa Ana, CA

More cities — Commercial real estate