Commercial Real Estate for Sale and Lease in San Luis Obispo, CA

Commercial property in San Luis Obispo, CA

Price on request

755 Fiero Lane, San Luis Obispo, CA

Industrial · 5,828 sqft · NNN lease · 98,881 sqft lot

This is a turn key R&D/Flex space consisting of hard offices, two large open work areas with 12’ ceilings, a conference room, break room, private restrooms and a warehouse space…

$3,250,000

1147 Marsh Street, San Luis Obispo, CA

Office · 4,634 sqft · Built 1964 · 4,707 sqft lot · Zoned O-Office

Welcome to the Ross Building - A luxury midcentury modern office building overlooking the San Luis Obispo creek and quietly tucked away in the northern part of the Downtown…

Price on request

1880 Santa Barbara, San Luis Obispo, CA

Office · 3,609 sqft · NNN lease · Built 2010 · 871 sqft lot

Prime office suites from +/-1,177 to +/- 3,609 of rentable square feet available for lease in the prominent Railroad Square Business Park.

Price on request

4120 Horizon G, San Luis Obispo, CA

Warehouse · 1,100 sqft · Modified gross lease · Built 1988 · 26,136 sqft lot

Very desirable end cap warehouse space located in South San Luis Obispo. The unit features 1,100 SF of shop space with a grade level roll-up door and private restroom.

Price on request

3426 Empresa 100, San Luis Obispo, CA

Office · 3,861 sqft · NNN lease · Built 2001 · 19,166 sqft lot

The office has a slate entry area, 10 private offices, conference room, kitchen, work areas, and IT room. The building is conveniently located near the Prado Road on/off ramps.

Price on request

3000 Broad Street 211/213, San Luis Obispo, CA

Office · 2,450 sqft · NNN lease · Built 1996 · 2,450 sqft lot

Two contiguous suites in very good condition. They can be leased together or separately. Suite 211 is 1,360 SF and suite 213 is 1,090 SF.

Price on request

12330 Los Osos Valley Road, San Luis Obispo, CA

Retail · 2,511 sqft · NNN lease · 104,108 sqft lot

Suite 12330 and 12332 are currently configured together totaling +/- 2,511 SF but can be leased separately.

Price on request

100 Cross Street, San Luis Obispo, CA

Office · 18,171 sqft · NNN lease · 102,366 sqft lot

100 Cross St. Located in the Higuera Center, this building sits at one of the main intersections in San Luis Obispo and offers a variety of office options for your business.

$8,621

857 Higuera Street, San Luis Obispo, CA

Retail · 2,330 sqft · Gross lease · 2,330 sqft lot · Zoned C-D

Downtown San Luis Retail/Restaurant Space. Approximately 2,330 SF ground-floor storefront on downtown San Luis Obispo's primary retail corridor.

$3,700,000

356 N Chorro, San Luis Obispo, CA

Multi Family · Price reduced · 9,360 sqft · Built 1983 · 14 units · 12,951 sqft lot · Zoned R4

Welcome to Leland Lofts, a 14-unit multifamily property in the heart of San Luis Obispo. Across three buildings, the property offers 12 studios, 2 one-bedroom residences with 1 1/2…

$495,000

1250 Peach St H, San Luis Obispo, CA

Office · 1,360 sqft · 1,360 sqft lot

1250 Peach is a well- appointed medical condo featuring four exam rooms, a physician’s office, private restrooms, a reception area, and onsite parking.

Price on request

4185 Earthwood, San Luis Obispo, CA

Retail · 7,831 sqft · Gross lease · 9,011 sqft lot

Strategically positioned in South San Luis Obispo, the development is surrounded by significant new residential and employment growth.

$8,448

3285 S Higuera Street, San Luis Obispo, CA

Industrial · 5,280 sqft · Modified gross lease · Built 1957 · 16,616 sqft lot · Zoned C-S-S

A freestanding +/-5,280 SF single-story industrial building on San Luis Obispo's South Higuera corridor - the city's primary service-commercial spine.

$2,500

429 Marsh, San Luis Obispo, CA

Office · 519 sqft · Modified gross lease · Built 2021 · 636 sqft lot

Turnkey executive office condominium in the heart of downtown San Luis Obispo. Built to a high-end, move-in-ready standard with warm wood-slat detailing, designer cabinetry, a…

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$559,000

429 Marsh, San Luis Obispo, CA

Office · 519 sqft · Built 2021 · 636 sqft lot

Turnkey executive office condominium in the heart of downtown San Luis Obispo. Built to a high-end, move-in-ready standard with warm wood-slat detailing, designer cabinetry, a…

Price on request

860 Walnut C, San Luis Obispo, CA

Office · 1,100 sqft · Gross lease · Built 1983 · 19,909 sqft lot

Second floor office space with three private offices, an open work area, a coffee bar, and a private restroom. A short walk to the downtown core and excellent freeway access.

$1,000,000

4115 Vachell, San Luis Obispo, CA

Mixed Use · Price reduced · 1,482 sqft · Built 1913 · 18,232 sqft lot · Zoned c-s comm svc

4115 Vachell Lane offers an exceptional investment opportunity for developers, owner-users, and commercial investors looking to secure a high-potential footprint in a highly…

Price on request

805 Aerovista Place 201, San Luis Obispo, CA

Office · 6,121 sqft · Gross lease · Built 2001 · 6,121 sqft lot

This second floor office suite is located in the rear building on Aerovista Place adjacent to the San Luis Obispo Regional Airport.

Price on request

277 South Street TY, San Luis Obispo, CA

Office · 6,562 sqft · Gross lease · Built 1985 · 33,977 sqft lot

This suite consists of several private offices and open space, with four restrooms, a large kitchen, two conference rooms, and a reception area..

$675,000

1551 Bishop 440, San Luis Obispo, CA

Office · 1,162 sqft · 1,162 sqft lot

1551 Bishop St, Suite 440 in San Luis Obispo is available for sale or lease within an established medical and professional office community.

Price on request

1551 Bishop 440, San Luis Obispo, CA

Office · 1,162 sqft · NNN lease · 1,162 sqft lot

1551 Bishop St, Suite 440 in San Luis Obispo is available for sale or lease within an established medical and professional office community.

$1,900,000

3437 Empresa, San Luis Obispo, CA

Office · 6,280 sqft · Built 1989 · 3 units · 6,280 sqft lot

Positioned in one of San Luis Obispo's established commercial corridors, this well-maintained multi-tenant office property presents an outstanding investment opportunity with…

Price on request

1065 Higuera 200, San Luis Obispo, CA

Office · 1,511 sqft · Modified gross lease · Built 1958 · 12,470 sqft lot

2nd floor professional office suite provides great natural light and Downtown City views. Located above BlackHorse Coffee in the heart of Downtown San Luis Obispo, just steps from…

$1,818,000

664 Marsh, San Luis Obispo, CA

Retail · Price reduced · 1,920 sqft · Built 1937 · 7,000 sqft lot

Distinctive tenant-occupied commercial investment opportunity in the heart of Downtown San Luis Obispo.

More listings in San Luis Obispo, CA

What's on the market in San Luis Obispo right now

Asking prices of listings currently active on Nalren in San Luis Obispo, CA, refreshed daily.

Commercial property types in San Luis Obispo

• Office: 17 for sale, 39 for lease · median asking $1,137,000 · for lease
• Retail: 7 for sale, 9 for lease · median asking $1,851,000 · for lease
• Industrial & Warehouse: 11 for lease · for lease
• Multifamily: 2 for sale
• Mixed-Use: 3 for sale, 1 for lease · median asking $3,465,000

All 60 commercial spaces for lease in San Luis Obispo →

Counts and asking prices of listings currently active on Nalren in San Luis Obispo, CA, refreshed daily. Asking prices, not valuations.

Recently sold commercial properties in San Luis Obispo, CA

By type: 19 office, 6 industrial & warehouse, 3 retail, 2 land, 2 mixed-use.

Latest closed sales

• 2040 Broad: Sold for $1,026,000 on Sep 24, 2026 (Office · 2,550 sqft)
• 1338 Santa Rosa Street: Sold for $1,650,000 on Sep 9, 2026 (Office · 3,861 sqft)
• 699 California: Sold for $1,820,000 on Aug 25, 2026 (Office · 3,000 sqft · 2 units)
• 285 Prado: Sold for $2,160,000 on Aug 25, 2026 (Warehouse · 8,486 sqft)
• 143 Suburban Road: Sold for $8,250,000 on Jun 11, 2026 (Industrial · 46,242 sqft)
• 1022 Mill Street: Sold for $1,200,000 on Apr 21, 2026 (Mixed Use · 2,471 sqft)
• 715 Higuera: Sold for $1,750,000 on Apr 1, 2026 (Retail · 2,160 sqft)
• 1124 Nipomo Street B: Sold for $1,100,000 on Mar 13, 2026 (Mixed Use · 1,900 sqft)
• 1304 Ella CD: Sold for $3,250,000 on Mar 2, 2026 (Office · 6,477 sqft)
• 2475 Victoria: Sold for $209,000 on Jan 23, 2026 (Retail · 1,073 sqft)

Sold prices are MLS-reported closed sales recorded in San Luis Obispo, CA over the last 24 months, not an estimate or valuation of any property.

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