Commercial Real Estate for Sale and Lease in San Luis Obispo, CA

Commercial property in San Luis Obispo, CA

Price on request

4185 Earthwood, San Luis Obispo, CA

Retail · 7,831 sqft · Gross lease · 9,011 sqft lot

Strategically positioned in South San Luis Obispo, the development is surrounded by significant new residential and employment growth.

$8,448

3285 S Higuera Street, San Luis Obispo, CA

Industrial · 5,280 sqft · Modified gross lease · Built 1957 · 16,616 sqft lot · Zoned C-S-S

A freestanding +/-5,280 SF single-story industrial building on San Luis Obispo's South Higuera corridor - the city's primary service-commercial spine.

$2,500

429 Marsh, San Luis Obispo, CA

Office · 519 sqft · Modified gross lease · Built 2021 · 636 sqft lot

Turnkey executive office condominium in the heart of downtown San Luis Obispo. Built to a high-end, move-in-ready standard with warm wood-slat detailing, designer cabinetry, a…

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$559,000

429 Marsh, San Luis Obispo, CA

Office · 519 sqft · Built 2021 · 636 sqft lot

Turnkey executive office condominium in the heart of downtown San Luis Obispo. Built to a high-end, move-in-ready standard with warm wood-slat detailing, designer cabinetry, a…

Price on request

860 Walnut C, San Luis Obispo, CA

Office · 1,100 sqft · Gross lease · Built 1983 · 19,909 sqft lot

Second floor office space with three private offices, an open work area, a coffee bar, and a private restroom. A short walk to the downtown core and excellent freeway access.

$1,200,000

4115 Vachell, San Luis Obispo, CA

Mixed Use · 1,482 sqft · Built 1913 · 18,232 sqft lot · Zoned c-s comm svc

4115 Vachell Lane offers an exceptional investment opportunity for developers, owner-users, and commercial investors looking to secure a high-potential footprint in a highly…

Price on request

805 Aerovista Place 201, San Luis Obispo, CA

Office · 6,121 sqft · Gross lease · Built 2001 · 6,121 sqft lot

This second floor office suite is located in the rear building on Aerovista Place adjacent to the San Luis Obispo Regional Airport.

Price on request

277 South Street TY, San Luis Obispo, CA

Office · 6,562 sqft · Gross lease · Built 1985 · 33,977 sqft lot

This suite consists of several private offices and open space, with four restrooms, a large kitchen, two conference rooms, and a reception area..

$675,000

1551 Bishop 440, San Luis Obispo, CA

Office · 1,162 sqft · 1,162 sqft lot

1551 Bishop St, Suite 440 in San Luis Obispo is available for sale or lease within an established medical and professional office community.

Price on request

1551 Bishop 440, San Luis Obispo, CA

Office · 1,162 sqft · NNN lease · 1,162 sqft lot

1551 Bishop St, Suite 440 in San Luis Obispo is available for sale or lease within an established medical and professional office community.

Price on request

799 Higuera, San Luis Obispo, CA

Retail · 1,800 sqft · Gross lease · 196,020,000 sqft lot

Ideal retail sublease space on the corner of Downtown San Luis Obispo’s two main thoroughfares. In addition to the 1800 SF ground floor retail space is a basement storage area.

$1,900,000

3437 Empresa, San Luis Obispo, CA

Office · 6,280 sqft · Built 1989 · 3 units · 6,280 sqft lot

Positioned in one of San Luis Obispo's established commercial corridors, this well-maintained multi-tenant office property presents an outstanding investment opportunity with…

Price on request

219 bonetti D, San Luis Obispo, CA

Warehouse · 2,100 sqft · NNN lease · 2,100 sqft lot

This warehouse unit has one roll-up door and is all open space. There is a corner restroom. On-site parking. Located close to the U.S. 101 Interchange.

Price on request

1065 Higuera 200, San Luis Obispo, CA

Office · 1,511 sqft · Modified gross lease · Built 1958 · 12,470 sqft lot

2nd floor professional office suite provides great natural light and Downtown City views. Located above BlackHorse Coffee in the heart of Downtown San Luis Obispo, just steps from…

$725,000

2241 Broad Street, San Luis Obispo, CA

Office · 923 sqft · Built 1905 · 4,500 sqft lot · Zoned Office

Secure the ultimate Central Coast headquarters with this highly functional 923 sq ft office near the SLO Airport. Broad St. is a high traffic and visibility corridor.

$2,000,000

664 Marsh, San Luis Obispo, CA

Retail · 1,920 sqft · Built 1937 · 7,000 sqft lot

Distinctive tenant-occupied commercial investment opportunity in the heart of Downtown San Luis Obispo.

$2,500,000

668 Marsh, San Luis Obispo, CA

Retail · 6,880 sqft · Built 1988 · 7,000 sqft lot

Multi-tenant retail and professional office investment opportunity in the heart of Downtown San Luis Obispo.

$2,000,000

1127 Broad, San Luis Obispo, CA

Retail · 3,718 sqft · Built 1910 · 5,000 sqft lot

Two-tenant commercial investment opportunity in the heart of Downtown San Luis Obispo. This approximately 3,718-square-foot Broad Street property features two occupied storefront…

$3,949,000

615 Clarion Court, San Luis Obispo, CA

Mixed Use · 13,184 sqft · Built 2004 · 21,834 sqft lot

13,184 SF modern warehouse/office building in San Luis Obispo, offering exceptional flexibility for either multi-tenant investment or owner-occupancy, in a popular modern…

Price on request

1327 Archer Street 220, San Luis Obispo, CA

Office · 4,512 sqft · Modified gross lease · 11,575 sqft lot

Incentive: First Year Rent $2.25 PSF Modified Gross Hard to find large, modern office suite near Downtown.

Price on request

1411 Marsh 203, San Luis Obispo, CA

Office · 936 sqft · NNN lease · Built 1988 · 936 sqft lot

The Marsh Street Pavilions is a multi-tenant, elevatorserved office building with subterranean parking.

Price on request

3474 Empresa 150, San Luis Obispo, CA

Office · 8,277 sqft · NNN lease · 8,277 sqft lot

Modern flex commercial space with office/warehouse and fenced yard with a storefront and rear roll-up doors. The facility is in immaculate condition.

Price on request

581 Higuera Street 100, San Luis Obispo, CA

Mixed Use · 4,000 sqft · NNN lease · 4,000 sqft lot

The Brickhouse Ground-Floor Restaurant Space | ±4,000 SF Shell | Outdoor Patio Available A dedicated ground-floor restaurant opportunity within the Brickhouse — a dynamic mixed-use…

$4,400,000

1150 Palm, San Luis Obispo, CA

Office · 9,767 sqft · Built 1986 · 21,037 sqft lot · Zoned Office

Exceptional opportunity to invest in a fully occupied office building in downtown San Luis Obispo.

More listings in San Luis Obispo, CA

What's on the market in San Luis Obispo right now

Asking prices of listings currently active on Nalren in San Luis Obispo, CA — refreshed daily.

Commercial property types in San Luis Obispo

• Office — 17 for sale, 36 for lease · median asking $887,500 · for lease
• Retail — 7 for sale, 10 for lease · median asking $1,947,500 · for lease
• Industrial & Warehouse — 11 for lease · for lease
• Multifamily — 1 for sale
• Mixed-Use — 3 for sale, 1 for lease · median asking $3,465,000

All 58 commercial spaces for lease in San Luis Obispo →

Counts and asking prices of listings currently active on Nalren in San Luis Obispo, CA — refreshed daily. Asking prices, not valuations.

Recently sold commercial properties in San Luis Obispo, CA

By type: 19 office, 6 industrial & warehouse, 4 retail, 3 land, 2 mixed-use.

Latest closed sales

• 1338 Santa Rosa Street — Sold for $1,650,000 on Sep 9, 2026 (Office · 3,861 sqft)
• 699 California — Sold for $1,820,000 on Aug 25, 2026 (Office · 3,000 sqft · 2 units)
• 285 Prado — Sold for $2,160,000 on Aug 25, 2026 (Warehouse · 8,486 sqft)
• 143 Suburban Road — Sold for $8,250,000 on Jun 11, 2026 (Industrial · 46,242 sqft)
• 1022 Mill Street — Sold for $1,200,000 on Apr 21, 2026 (Mixed Use · 2,471 sqft)
• 715 Higuera — Sold for $1,750,000 on Apr 1, 2026 (Retail · 2,160 sqft)
• 1124 Nipomo Street B — Sold for $1,100,000 on Mar 13, 2026 (Mixed Use · 1,900 sqft)
• 1304 Ella CD — Sold for $3,250,000 on Mar 2, 2026 (Office · 6,477 sqft)
• 2475 Victoria — Sold for $209,000 on Jan 23, 2026 (Retail · 1,073 sqft)
• 870 Osos Street — Sold for $850,000 on Jan 20, 2026 (Office · 1,418 sqft)

Sold prices are MLS-reported closed sales recorded in San Luis Obispo, CA over the last 24 months — not an estimate or valuation of any property.

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