Commercial Real Estate for Sale and Lease in San Mateo, CA
Find commercial real estate across San Mateo, CA — office space, retail storefronts, industrial buildings, warehouses, and mixed-use. Compare asking prices and lease rates, view photos, and connect with the listing brokerage.
Commercial property in San Mateo, CA
$1,999,000
228 State Street, San Mateo, CA
4,556 sqft · Built 1926 · 7,500 sqft lot · Zoned RM0000
Excellent five-unit investment opportunity ideally located between Downtown San Mateo and Downtown Burlingame, offering convenient access to shopping, dining, Caltrain, major…
$2,495,000
616 S Amphlett Boulevard, San Mateo, CA
6,098 sqft · Built 1935 · 6,020 sqft lot · Zoned CH00C4
616 S Amphlett Blvd represents a unique opportunity to acquire a well-located mixed-use investment property in the heart of San Mateo.
$1,100,000
180 South Boulevard, San Mateo, CA
1,834 sqft · Built 1948 · 4,767 sqft lot · Zoned c2-1
$4,998,000
1101 Tilton Avenue, San Mateo, CA
7,756 sqft · Built 1954 · 8,565 sqft lot · Zoned R3
1101 Tilton Ave is a stunning 12-unit apartment community located in the thriving city of San Mateo, California.
$1,648,000
869 WOODSIDE WAY, San Mateo, CA
Built 1942 · 5.88% cap rate · 2,222 sqft lot · Zoned ML00
Recently remodeled (2023) and never occupied commercial space, offering a rare move-in ready mixed-use opportunity in the heart of San Mateo Village and a central Peninsula…
$2,000,000
168 W 25th Avenue, San Mateo, CA
2,837 sqft · Built 1968 · 3,049 sqft lot · Zoned CL0C11
$8,900,000
100106 N Bayshore Boulevard, San Mateo, CA
Price reduced · 24,592 sqft · Built 1960 · 38 units · 24,944 sqft lot · Zoned Commercial Multifamily
PRICE REDUCTION of $550,000! -- The Knights Inn Apartments, located at 100-106 N. Bayshore Boulevard in San Mateo, presents a rare 38-unit multifamily investment opportunity in San…
$2,500,000
San Mateo, CA 94402
Price reduced · 5,624 sqft · Built 1958 · 7 units · 7,728 sqft lot · Zoned R3
Fiesta Gardens Six unit building in very good condition. Upper units have decks; lower units have patio yards.
$3,600
San Mateo, CA 94401
Mixed Use · Built 1960 · 1,800 sqft lot · Zoned Comm
Commercial Store, Market uses, Shop Space or Tech Space lots of opportunity uses for this close in space to Downtown Burlingame and San Mateo.
$875,000
255 N San Mateo Drive Suite 2
900 sqft · Built 1960 · 8,481 sqft lot · Zoned EA00E2
Welcome to 255 N. San Mateo Drive, Suite 2 in San Mateo, California. This is a rare opportunity to own your very own medical/dental office suite close to Downtown San Mateo.
$12,000
2575 Flores Street, San Mateo, CA
Mixed Use · Built 1962 · 6,442 sqft lot · Zoned C10001
SC Properties is proud to present 2575 Flores Street, a thoughtfully renovated office opportunity in the heart of San Mateo on 25th Ave.
$20,230
1009 S Claremont Street, San Mateo, CA
Mixed Use · Built 1989 · 5,350 sqft lot · Zoned ML00M
2 story building w/auto garage door. Separate computer server rooms w/independent HVAC systems. Alarm systems. Camera surveillance inside & out. Electronic door access system.
$2,150,000
216 N San Mateo Drive
Price reduced · 2,796 sqft · Built 1900 · 8,409 sqft lot · Zoned EA00E2
$1,899,000
19 E 41st Place, San Mateo, CA
Price reduced · 2,447 sqft · Built 1957 · 6 units · 7,699 sqft lot · Zoned R4
19 E 41st Place is a well-maintained six-unit multifamily asset in the desirable San Mateo submarket.
$2,750,000
739 N Amphlett Boulevard, San Mateo, CA
Price reduced · 4,586 sqft · Built 1958 · 6 units · 4,313 sqft lot · Zoned R40000
An exceptional investment opportunity in the heart of San Mateo! This commercial multi-unit property at 739 N.
$3,000,000
420 Peninsula Avenue 2, San Mateo, CA
4,000 sqft · Built 2024 · 12,197 sqft lot · Zoned EA00E2
This newly built medical dental condo is situated on the bustling San Mateo - Burlingame border. Condo is thoughtfully renovated with quality material and finishes throughout.
$3,675
153 E 5th Avenue, San Mateo, CA
Mixed Use · Built 1958 · 3,850 sqft lot · Zoned CB000D
Prime commercial lease opportunity in Downtown San Mateo, fantastic location across from Central Park!
$5,425,000
735 N Amphlett Boulevard, San Mateo, CA
Price reduced · 4,586 sqft · Built 1958 · 12 units · 4,313 sqft lot · Zoned R40000
An exceptional investment opportunity in the heart of San Mateo! This commercial multi-unit property at 735 & 739 N.
$6,320
931 N Amphlett Boulevard, San Mateo, CA
Mixed Use · Price reduced · Built 1960 · 5,654 sqft lot · Zoned CH00C4
Versatile Commercial Warehouses in San Mateo: Ideal for Logistics, Office, or Light Industrial.
$3,500
420 Peninsula Avenue 3, San Mateo, CA
Mixed Use · Price reduced · Built 2019 · 12,212 sqft lot · Zoned EA00E2
This newly constructed medical/dental condo is ideally located on the vibrant San Mateo - Burlingame border.
$2,150,000
3939 Pacific Boulevard, San Mateo, CA
5,016 sqft · Built 1958 · 5 units · 6,264 sqft lot · Zoned MFD
Rarely Available Opportunity to Acquire 5-unit Spacious, Easy-To-Manage apartment building consisting of four 1-bed 1-bath and one 2-bed 1-bath.
$3,600
420 Peninsula Avenue 2, San Mateo, CA
Mixed Use · Price reduced · Built 2019 · 12,212 sqft lot · Zoned EA00E2
This newly constructed medical/dental condo is ideally located on the vibrant San Mateo - Burlingame border.
$3,000,000
420 Peninsula Avenue 3, San Mateo, CA
4,000 sqft · Built 2019 · 12,212 sqft lot · Zoned EA00E2
This newly constructed medical/dental condo is ideally located on the vibrant San Mateo Burlingame border.
Showing 23 listings in San Mateo, CA — open the app for the full catalog.
What's on the market in San Mateo right now
16
Listed for sale now
7
For lease now
Asking prices of listings currently active on Nalren in San Mateo, CA — refreshed daily.
Commercial property types in San Mateo
- Mixed-Use — 7 for lease
All 7 commercial spaces for lease in San Mateo →
Counts and asking prices of listings currently active on Nalren in San Mateo, CA — refreshed daily. Asking prices, not valuations.
Recently sold commercial properties in San Mateo, CA
10
Closed sales (last 24 months)
$2,235,000
Median sold price
$410
Median sold price per sqft
Latest closed sales
- 125 South Boulevard — Sold for $3,300,000 on Aug 11, 2026 (10,707 sqft)
- 20012003 Parrott Drive — Sold for $5,650,000 on Jul 8, 2026 (14,316 sqft)
- 2830 Flores Street — Sold for $8,225,000 on Jan 22, 2026 (15,311 sqft)
- 1950 Ivy Street — Sold for $2,060,000 on Dec 30, 2025 (4,428 sqft)
- 128 N B Street — Sold for $1,279,750 on Dec 12, 2025 (1,400 sqft)
- 1956 Ivy Street — Sold for $2,049,000 on Nov 21, 2025 (4,192 sqft)
- 320 N San Mateo Drive 2 — Sold for $150,000 on Oct 17, 2025 (3,726 sqft)
- 231 Villa Terrace — Sold for $3,900,000 on Jul 21, 2025 (11,260 sqft)
- 43 N Idaho Street — Sold for $1,748,000 on Dec 30, 2024 (4,116 sqft)
- 1110 Haddon Drive — Sold for $2,410,000 on Oct 31, 2024 (6,540 sqft)
Sold prices are MLS-reported closed sales recorded in San Mateo, CA over the last 24 months — not an estimate or valuation of any property.
Commercial real estate in cities near San Mateo
Commercial real estate guides
Buying, selling, or leasing commercial property in San Mateo, CA?
Tell us what you're working on and a licensed Nalren agent — or, in some cases, a licensed referral partner — who works commercial real estate reaches out, typically within one business day. Free, no obligation.
Frequently asked questions — San Mateo, CA
Is there commercial space for lease in San Mateo, CA?
Yes — Nalren currently lists 7 commercial spaces for lease in San Mateo, CA (7 mixed-use). Lease rates vary by term and structure (NNN vs. gross), so compare per-listing terms and contact the listing brokerage directly.
What have commercial properties sold for in San Mateo, CA?
10 commercial properties closed in San Mateo, CA in the last 24 months, from $150,000 to $8,225,000 with a median sold price of $2,235,000 and a median of $410 per square foot. These are MLS-reported closed sales — not an estimate or valuation of any property.
How many commercial real estate listings are in San Mateo, CA?
Nalren currently has 23 commercial real estate listings in San Mateo, CA. New listings are added throughout the day — open the Nalren app to see everything and set alerts.